I'm not quite crazy enough to say that epinephrine will help you survive the inevitable zombie apocalypse (you can go here for that). I'm just suggesting in a roundabout way that if you happened to be in a situation where something was trying to eat you, the increased heart rate and blood flow to your muscles brought on by a well-timed dose might just save your life.
It seemed important to know if this all-encompassing negativity was histrionic or appropriate — that is, if the hard-core Preppers I had met were crazy or were, in fact, on to something. Just before the show-and-tell, I came across a news report about Dr. Irwin Redlener, the director of the National Center for Disaster Preparedness at Columbia University, whom Gov. Andrew M. Cuomo had recently named to lead a commission investigating how ready the state was for another Hurricane Sandy-like emergency. I arranged an interview, figuring that he, if anyone, could answer my question.
Mainstream economist and financial adviser Barton Biggs is a proponent of preparedness. In his 2008 book Wealth, War and Wisdom, Biggs has a gloomy outlook for the economic future, and suggests that investors take survivalist measures. In the book, Biggs recommends that his readers should "assume the possibility of a breakdown of the civilized infrastructure." He goes so far as to recommend setting up survival retreats:[52] "Your safe haven must be self-sufficient and capable of growing some kind of food," Mr. Biggs writes. "It should be well-stocked with seed, fertilizer, canned food, medicine, clothes, etc. Think Swiss Family Robinson. Even in America and Europe, there could be moments of riot and rebellion when law and order temporarily completely breaks down."[22]

MY OWN ATTEMPTS at prepping started at a point between the fall of Lehman Brothers and the corresponding rise of quantitative easing, when it occurred to me — as, of course, it did to many — that the financial system was appallingly unstable and that the realm of the possible now included a disruptive reduction in the value of our money. Egged on by admittedly heated readings of doomsday authors like John Mauldin and Charles Hugh Smith, I began to form a picture of the world as a system of unsustainable systems, a rickety Rube Goldberg machine in which the loss of any one piece — cheap oil, say — could derail the whole contraption, from truck transportation to the distribution of food.
Sticking around when there is at least a 50% chance of a disaster occurring (hurricane, flood, landslides, tsunami, wildfire) is just plain silly.  Part of your planning should be to determine the trigger point for evacuation as well as identification of an evacuation site and a route to get there.  Better yet, plan multiple alternate routes as well.
For global catastrophic risks the costs of food storage become impractical for most of the population [53] and for some such catastrophes conventional agriculture would not function due to the loss of a large fraction of sunlight (e.g. during nuclear winter or a supervolcano). In such situations, alternative food is necessary, which is converting natural gas and wood fiber to human edible food.[54]
This bug-out motorbike may be just what a city dweller needs to run for the hills, with its ability to weave through traffic around miles of cars with occupants also trying to escape. Its oversized universal rack accepts bolt-ons to mount survival gear or harnesses of the rider’s choice, and with the addition of two optional fuel tanks, this baby can go for 250-300 miles before you’ll have to battle other looters of abandoned vehicles to get more gas.
Update: Yes, if you have prescription meds you’d die or suffer without, definitely pack an extra few weeks’ worth in your go-bag. And stick in extra glasses for anyone who wears prescription lenses. I didn’t add these because the former doesn’t apply to me, and I haven’t gotten around yet to buying the latter, but commenters have reminded me that these two things are at the top of the FEMA list.
Today, Luther says she keeps a pantry with three different levels of “defense.” The first consists of boxes of cereal, frozen foods, and other items you might fall back on if you couldn’t make it to the grocery store for a week or two. The second, her “short-term” food storage, includes canned goods and other items with a longer shelf life — “Stuff you’d use if perhaps you lost a stream of income and times were tight for a few months,” Luther explains. The third is her long-term food storage: Mylar bags full of dry goods like beans, rice, and wheatberries, as well as some freeze-dried fruits, vegetables, and meat. Layer three, she says, is for “a situation in which all hell has broken loose.”
What’s the bare minimum you need to navigate across land?  For most people, that would be a compass and map.  A basic road map is sufficient to get a rough approximation of the lay of the land.  More detailed relief maps can help plan for elevation and estimate possible water sources but they also take up more room in your pack.  Waterproofed or laminated maps are also extremely helpful.  Lensatic compasses are the most reliable for little money.  If possible, a compass and protractor are also extremely helpful for route planning.  Obviously, not as essential but nonetheless useful.